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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC1L
All Species:
19.39
Human Site:
T453
Identified Species:
35.56
UniProt:
Q13415
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13415
NP_004144.2
861
97350
T453
S
L
K
S
S
L
H
T
L
T
K
V
P
K
K
Chimpanzee
Pan troglodytes
XP_513408
861
97367
T453
S
L
K
S
S
L
H
T
P
T
K
V
P
K
K
Rhesus Macaque
Macaca mulatta
XP_001111614
860
97440
T452
S
L
K
S
S
L
Y
T
P
T
K
M
P
K
K
Dog
Lupus familis
XP_532575
858
97161
T451
S
M
K
S
S
L
Q
T
P
S
K
T
P
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N2
840
95057
T432
G
Q
S
R
T
R
Q
T
P
S
K
S
P
Q
K
Rat
Rattus norvegicus
Q80Z32
848
95741
T440
A
S
K
P
S
S
Q
T
P
S
K
S
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026457
858
96850
K451
P
S
V
H
T
P
A
K
T
P
R
K
T
P
L
Frog
Xenopus laevis
NP_001081806
886
99953
T479
T
P
T
S
S
R
K
T
S
S
R
T
P
N
K
Zebra Danio
Brachydanio rerio
NP_956227
910
101179
K502
V
S
A
R
T
P
C
K
T
P
S
K
K
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16810
924
103263
P517
I
T
T
A
T
A
T
P
M
T
P
S
Q
K
M
Honey Bee
Apis mellifera
XP_392056
490
55682
K99
T
P
K
S
H
S
I
K
C
S
N
L
I
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798977
905
100707
L490
L
I
V
D
E
L
D
L
L
W
T
R
K
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567440
809
91877
H413
I
P
E
H
V
R
C
H
K
Q
S
E
L
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
81.5
N.A.
66
69.8
N.A.
N.A.
50.5
52.4
48.6
N.A.
33.4
31.8
N.A.
29.7
Protein Similarity:
100
98.9
97.3
88.8
N.A.
77.9
79.9
N.A.
N.A.
66.3
67
63.1
N.A.
52.7
43.5
N.A.
47.1
P-Site Identity:
100
93.3
80
66.6
N.A.
26.6
46.6
N.A.
N.A.
0
33.3
0
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
46.6
60
N.A.
N.A.
13.3
53.3
6.6
N.A.
33.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
16
8
0
16
8
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
47
0
0
0
8
24
8
0
47
16
16
47
62
% K
% Leu:
8
24
0
0
0
39
0
8
16
0
0
8
8
0
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
8
24
0
8
0
16
0
8
39
16
8
0
54
16
0
% P
% Gln:
0
8
0
0
0
0
24
0
0
8
0
0
8
16
0
% Q
% Arg:
0
0
0
16
0
24
0
0
0
0
16
8
0
0
0
% R
% Ser:
31
24
8
47
47
16
0
0
8
39
16
24
0
0
8
% S
% Thr:
16
8
16
0
31
0
8
54
16
31
8
16
8
0
0
% T
% Val:
8
0
16
0
8
0
0
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _